Archive for the ‘Topical Finasteride’ Category

TOPICAL FINASTERIDE ON CLINICAL TRIAL

Thursday, July 8th, 2010

Androgenic Alopecia is a popular type of hair loss in both men and women alike.  Usually called as Male Pattern Baldness in male. Nevertheless, the pattern of baldness on women is very different from those of men; hair loss of women does not usually end up bald. The thinning of their hair start off all over the head and the hairline looks as if it does not retreat; thinning of hair is more likely to happen. Fortunately, a medical study introduced the most effective treatment for androgenic alopecia, called Topical Finasteride, is a much better alternative to those who does not want to take oral medicines.

The actual composition of the said medication, topical finasteride was water, propylene glycol and ethanol in the percentage of 25%, 25% and 50% in particular substance. The actual results of the said experiment were being photographed every month for easy comparison of both topical and oral finasteride treated subjects. The outcomes were purposely evaluated by sections and then weigh against those photos taken during the final part of the trial time that is on the 16th month thereafter.

Evidently, different levels acknowledge for assessment are as follows, full recovery of hair fullness, apparent bald spot diminishes, the increase of size of bald spots and also contains no result at all. Thus, the reaction of the various clinical levels of the said clinical study made no impact on the first three months of application. However, throughout the full coverage of finasteride trial, the condition of the patients pertaining to hair loss becomes remarkably progressive particularly the orally taken Finasteride medication. The feedback of the studied treatment was legitimized through the outcome of an excessive hair density on the exterior sides of the bald spots. As the finasteride probationary was in progress, the reaction of patients produced a type of hair that can readily converts to strong and stained terminal hair. Concerning to those patients treated with topical finasteride, many failed because of scarcity of positive results compare to the latter in the condition of scalp hair. However, there is a chronological ratio of the growth of the hair thickness and the terminal calculation of hair among each group. Finally, they concluded somehow that its respective difference is the same base on the trial observation of both types of finasteride. In fact, the restorative end outcome of the two experimental drugs, topical finasteride and oral finasteride proves to bear no difference with each other rather; both have similar effects after all. Furthermore, a more thorough and broader scale of topical finasteride trial will be conducted for a more credible positive outcome in the future. These facts are base on “Topical Finasteride on Clinical Trial” performed.

Topical Finasteride – Minoxidil for topical medication

Friday, July 2nd, 2010

Iran executed its latest clinical study which primarily exhibits about the role and function of the topical Finasteride. Study confirmed the claims that these topical Finasterides in topical gel form are equally effective as with those Finasterides taken orally. Their efficacy is similar, impressively treating the male-patterned baldness. The test was done randomly which last for around 6 months, having 45 males as the subject. These men were recorded to experience baldness within 1.5 to 2 years.

The serial counts showed a valuable growth in the thickness of the hair as well as on the terminal hair measurements in two groups. The study then made the analysis that as an effect of the medication, no valuable dissimilarities exist in both groups with respect to the area size of balding, hair thickness, and hair measurements. Thus, therapeutic effects for Finasteride pill and Finasteride gel are relatively alike. Nevertheless, in one way or another, it may still matter what you will use since there is no presentation made yet that contains their side effect comparison.

One specific Finasteride‘s topical medication is Minoxidil, which is distributed through its brand name “Rogaine”. This drug has been known to stimulate the hair growth among old women and men. This is basically applied on the user’s scalp. The kind of medication that is applied in the body makes the topical medication. Minoxidil is distributed in the United States without any prescription. However, the specific method through which the drug performs is not yet identified.

There are only rare cases for side effects to occur upon using the Minoxidil. These side effects include headaches, lowered sexual performance or desire, rashes or itchiness in the scalp, chest pains or abnormal heartbeat, and dizzy spells. In addition, Minoxidil users are reminded not to mix the drug with the corticosteroids topical application since the application of these drugs right on the user’s scalp can lead to extreme minoxidil absorption.

Many people love the effects brought by Minoxidil. It stimulates the growth of the hair ranging from 10 percent up to 20 percent. Hair loss is minimized up to 90 percent. Normally, the growth of hair can only be noticed after several months of application.

This Minoxidil drug can’t be taken by all people. Others are prohibited from using it. People who have issues on irritation, high-blood pressure, or heart disease cannot be allowed to use Minoxidil because further serious ailments can occur if they insist to use the drug. Users must bear in mind though that if they want to keep and enjoy the benefits of Minoxidil in growing their hair, they shouldn’t discontinue their usage of Minoxidil.

Topical Finasteride products can also work impressively. If you do not want to end up regretting with your choice, then why not do your research first before you start your topical medication. There are several resources to verify credibility and functionality of your drug. Minoxidil itself was first recognized to treat high-blood pressure but then later recognized to also affect hair growth. Later, it was formulated as lotion for a direct scalp application.

Topical Finasteride – A Clinical Scope!

Friday, May 28th, 2010

A certain topical finasteride study over oral finasteride patients has been cited as a potential treatment for androgenic alopecia, this is a common form of hair loss in human both male and female. It is known as male pattern baldness in male wherein the hair starts to thin on top of the head and often only a frame of hair are left on the sides of the head. But the pattern of hair loss in women is a whole lot different than those of male. For the women, the thinning of hair takes place all over the head and it seems that the hairline does not move away and this does not often lead to baldness.

The available components for the topical finasteride study were water, propylene glycol and ethanol in the percentage of 25%, 25% and 50% in a respective manner. By a shoot up photographs every month, the result was deliberately measured by part and then eventually compared the photos during the end of the 16th month trial period by the groups being treated with oral finasteride and those with topical finasteride treated patients. Apparently, it was evaluated on several varying degrees including a complete restore of hair thickness, reduction of marked bald areas, enlargement of the bald areas and if there is no change compared to the baseline.

Consequently, the response on a clinical level was of no significant for the first 3 months. There has no significant difference from the study groups for the scores of hair re-growth. But throughout the course of the clinical study, the status with regards to the scalp hair has showed significant improvement among the oral finasteride patients. The response to the treatment has been authenticated by an increase in both hair densities on the outside edge of the balding areas. As the clinical response was progressing, the patients have produced vellus hair type which tends to transform to thick and pigmented or stained terminal hair. With regards to the patients receiving topical finasteride, there were a high number of dropouts due to the shortage of any improvement over the standing in the status of the scalp hair.

Hence, there is a sequential proportion pointed towards increase in the thickness of the hair and terminal counts of hair in each groups. It came to a conclusion that the conducted study over the result of the treatments shows no significant difference over the two groups. Apparently, the therapeutic end products of both topical finasteride and oral finasteride have been considered to be of similar effects to each other.  But in relation to the side effects, there has no provision of comparison to both groups. To conclude there should be more studies to be conducted regarding topical finasteride on a larger scale to be able to confirm a more positive result. The question now would close to this, are there more similar studies that similar dosage  will show the effects of topical finasteride over the oral one that would due to systematic absorption?


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