Archive for the ‘About FInasteride’ Category

What Is Finasteride?

Thursday, May 27th, 2010

Finasteride is a synthetic antiandrogen that acts by inhibiting the enzyme that converts testosterone to dihydrotestosterone .Finasteride was initially approved as a treatment for benign prostatic hyperplasia also known as enlarged prostate at a 5mg dosage once a day and was later  approved for treating male pattern baldness. Finasteride is also used in treating prostate cancer It would take a minimum of six months of medication to see the full effects of finasteride. If finasteride medication is stopped, any health benefit will be reversed. Finasteride may help eradicate the signs linked with enlarged prostate such as difficulty urinating, frequent urination during the night, vacillation at the start of urination, and decreased amount of urinary flow.

In a study conducted for men with mild to moderate hair loss, almost half of those treated with finasteride experienced regrowth of hair, and the remaining others had no further loss. Average hair count in treated with finasteride stayed above baseline, and sowed an increasing difference from hair count in the placebo group for the rest of the study. Finasteride is effective only for as long as it is taken; the hair gained is lost within 6–12 months of medication.

There are pills that are coated to prevent direct contact with the active ingredient. The dust particles from broken tablets should also be kept away from pregnant women. Some kind of finasteride has been ineffective for treating hair loss in women. Doctors may prescribe it for women, but not without adequate birth control measures in the event that the woman cannot be pregnant.

The use of finasteride to prevent prostate cancer is still debatable and controversial. Some doctors think that finasteride can stop the cancer but others think that it just minimizes small minor tumors that would not be fatal, and may even delay detection of cancers until they become major grade cancer.

Trials conducted showed that daily dosage of 5 mg, as is normally prescribed for people suffering from benign prostatic hyperplasia had lesser chance of having developed prostate cancer at the end of the trial compared to those who only took placebo. The study showed that finasteride increased the specificity and selectivity of prostate cancer exposure, thus producing a noticeable rate increase of high grade tumor. A recent update of this study found that finasteride decreases the occurrence of prostate cells by as much as 30%. In study conducted, the result was that the smaller prostate caused by finasteride means that a doctor is more likely to find cancer layers and more likely to find aggressive cells. Most of the men in the study who had cancer — aggressive or the passive type — decided to be treated; most of them had their prostates removed. A pathologist then examined thoroughly each of those persons who have prostate cancer who participated in the study and compared the kinds of cancers found at surgery to those diagnosed earlier. This study concluded that the risk of having high grade prostate cancer among the participants did not increase.


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